Cancer is a disease that is steadily on the rise in Kenya despite the fact that two-thirds of the prevalence is due to preventable causes. The study was carried out in two phases. In the first phase, a baseline survey was carried out in Kangemi a slum in Nairobi County. . In the second phase, laboratory analysis used a factorial design. The two treatments assessed were, cooked vegetables, raw vegetables, against a control on mice model. The association between gender and cancer screening was significant (χ28.034, DF=1, P=0.005). There was a significant association between occupation and cancer screening (χ228.158, DF=6, P=0.000). There was a significant relationship between knowing the benefits of leafy vegetable consumption and cooking time (U=33, p=0.008). In the second phase, the antioxidant activity of African nightshade leafy vegetable significantly increased when cooked (t=43.57, P= 0.000). In addition, expression of the urokinase plasminogen activator protein was reduced in mice fed with cooked vegetables by about 97% while the mice fed on raw vegetable expression was down-regulated by about 39% as compared to the control.
